|
KMID : 1114620100070010016
|
|
Journal of the Korean Society for Breast Screening
2010 Volume.7 No. 1 p.16 ~ p.22
|
|
|
False Negative Cases at Preoperative Breast MRI of Screening-Detected Breast Cancer
|
|
Moon Jeung-Hee
Han Boo-Kyung
Ko Eun-Young
Shin Jung-Hee
|
|
|
Abstract
|
|
|
Purpose: To characterize MR negative breast cancer during preoperative evaluation of cancers detected by combined screening with mammography and US.
Materials and Methods: During a year, we conducted preoperative MRI in consecutive 261 asymptomatic patients with breast cancers detected by mammography and US combined screening between January and December 2008. These cancers comprised of 173 screening mammography-detected cancers (SMDC) and 88 supplementary US-detected cancers (SUDC) that were occult on mammography. Two radiologists retrospectively searched MR negative breast cancers that were not able to be diagnosed as malignancy. Reasons for MR false negativity in 24 cases were assessed through imaging and pathology correlation.
Results: Among 24 false negative MR, reasons for MR negativity were followed as; gradually or faintly enhancing tiny focus (n= 11), multiple similar nodules in surrounding parenchyma (n=4), diffusely enhanced parenchyma (n=3), mildly enhanced mass or focal area including non-mass (n=3), no enhancement (n=3), technically inadequate examination (n=1). Among 9 mammographically detected cancers, 2 were not recognized on US and the rest 7 were seen also on US, and 15 US detected cancers were detected only by US. Histopathologic results were ductal carcinoma in situ (DCIS) in 15, invasive ductal carcinoma in 6, and invasive lobular carcinoma in 3.
Conclusion: US-only detected cancers are often false negative at MRI. Although MR negative cancers are pathologically more DCIS than invasive cancer, some invasive cancers could be occult on MR images due to variable causes.
|
|
|
KEYWORD
|
|
|
False-negative case, Breast cancer, MRI
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|